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Full scores ; Berlin: Bote & Bock, 1912. Full Scores (1); Parts (0); Vocal Scores (4). Pages with MssAu template Document 1 of 9: Original manuscript Full Score of the Orchestral work Full Score "Second German version" Scores published by Bote & Bock References Category:19th-century classical composers Category:German classical composers Category:German classical violinists Category:German conductors (music) Category:German male conductors (music) Category:19th-century German composers Category:1831 births Category:1916 deaths Category:German male classical composers Category:19th-century German male musicians Category:19th-century male musiciansDownregulation of microRNA-139-5p accelerates inflammatory injury in cardiac myocytes via regulation of microRNA-21-5p. MicroRNAs (miRNAs) participate in the regulation of cardiac myocyte inflammation. miR-21-5p promotes cardiac myocyte inflammation. However, the role of miR-139-5p in cardiac myocyte inflammation remains unclear. The aim of this study was to determine the role of miR-139-5p in cardiac myocyte inflammation. Cardiac myocytes were isolated from wild-type C57BL/6 mice (miR-139-5p-WT) or miR-139-5p knockout (miR-139-5p-KO) mice. Cardiac myocyte inflammation was induced by endotoxin LPS (10 μg/mL) treatment for different time periods. miR-139-5p, miR-21-5p, and targets were determined by quantitative real-time polymerase chain reaction (qRT-PCR) and Western blot. Cell apoptosis was assessed using the MTT and JC-10 methods. Enzyme-linked immunosorbent assay (ELISA) was performed to determine the pro-inflammatory cytokines levels. A luciferase reporter assay was performed to determine the regulatory relationship between miR-139-5p and PTEN. Inflammation was induced in isolated primary cardiac myocytes of miR-139-5p-WT and miR-139-5p-KO mice. Compared to miR-139-5p-WT cardiac myocytes, miR-139-5p-KO cardiac my
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